Diet and urine acidity may have roles in UTI susceptibility


The acidity of urine — as well as the presence of small molecules related to diet — may influence how well bacteria can grow in the urinary tract, a new study shows. The research, at Washington University School of Medicine in St. Louis, may have implications for treating urinary ... Read More »

Gerontology expert works to understand 'whole picture of aging'


Nancy Morrow-Howell , PhD, is a national leader in gerontology, widely known for her work on productive and civic engagement of older adults. She is the Bettie Bofinger Brown Distinguished Professor of Social Policy at the Brown School, faculty director of productive aging research at the  Center ... Read More »

Molecular biologist seeks the keys to healthy aging


As Shin-ichiro Imai grew up outside Tokyo, he heard his parents many times tell the story of his unlikely birth. According to Imai, doctors told his mother there was a high risk of losing the pregnancy because of a partially detached placenta. Imai’s mother went to great lengths to ... Read More »

Depression, behavioral changes may precede memory loss in Alzheimer’s


Depression and behavioral changes may occur before memory declines in people who will go on to develop Alzheimer’s disease, according to new research at  Washington University School of Medicine  in St. Louis. Researchers have known that many people with Alzheimer’s experience depression, irritability, apathy and appetite ... Read More »

Not all obese people develop metabolic problems linked to excess weight​​​​


New research demonstrates that obesity does not always go hand in hand with metabolic changes in the body that can lead to diabetes, heart disease and stroke.  In a study at  Washington University School of Medicine  in St. Louis, researchers found that a subset of obese people do ... Read More »

Natural compound helps reverse diabetes in mice" — Washington University Record


Researchers at Washington University School of Medicine in St. Louis have restored normal blood sugar metabolism in diabetic mice using a compound the body makes naturally... Read More »

Genetic variant linked to blocked heart arteries in patients with diabetes


Researchers at Washington University School of Medicine in St. Louis have identified the first genetic variant associated with severity of coronary artery disease in patients with type 2 diabetes. Read More »

Perhaps a longer lifespan, certainly a longer 'healthspan'”: Calorie restriction leads scientists to molecular pathways that slow aging, improve health


Organisms from yeast to rodents to humans all benefit from cutting calories. In less complex organisms, restricting calories can double or even triple lifespan. It’s not yet clear just how much longer calorie restriction might help humans live, but those who practice the strict diet hope to survive past 100 ... Read More »

Longer Life Foundation grants announced: Studies look to improve quality of life among elderly


The Longer Life Foundation has awarded grants to six research projects on issues related to aging at Washington University School of Medicine. Read More »

Longer Life Foundation awards five grants, seeks applications


The Longer Life Foundation, a cooperative effort between the School of Medicine and the Reinsurance Group of America (RGA), has awarded grants to five Washington University research projects looking at the genetics of aging, the effects of calorie restriction on aging and longevity, the relationship between cancer and aging, and ... Read More »